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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15397 | GNE-049 | Epigenetic Reader Domain | |
GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay). GNE-049 also inhibits BRET and BRD4(1) (IC50s: 12 nM and 4200 nM, respectively). | |||
T39352 | Piperidine-GNE-049-N-Boc | ||
Piperidine-GNE-049-N-Boc is a ligand that specifically binds to the target protein dCBP, enabling it to be degraded by a selective and potent heterobifunctional degrader, p300/CBP. |